| Club: | Frosinone |
| Season: | 2020–21 |
| Chairman: | Maurizio Stirpe |
| Manager: | Alessandro Nesta (until 22 March) Fabio Grosso (from 23 March) |
| Stadium: | Stadio Benito Stirpe |
| League: | Serie B |
| League Result: | 10th |
| Cup1: | Coppa Italia |
| Cup1 Result: | Second round |
| Pattern B1: | _frosinone2021h |
| Body1: | F7FE2E |
| Pattern La1: | _frosinone2021h |
| Leftarm1: | F7FE2E |
| Pattern Ra1: | _frosinone2021h |
| Rightarm1: | F7FE2E |
| Pattern Sh1: | _frosinone2021h |
| Pattern So1: | _frosinone2021h |
| Socks1: | ffe500 |
| Pattern B2: | _frosinone2021a |
| Body2: | FFFFFF |
| Pattern La2: | _frosinone2021a |
| Leftarm2: | FFFFFF |
| Pattern Ra2: | _frosinone2021a |
| Rightarm2: | FFFFFF |
| Pattern Sh2: | _frosinone2021a |
| Shorts2: | FFFFFF |
| Pattern So2: | _frosinone2021a |
| Socks2: | FFFFFF |
| Pattern La3: | _frosinone2021t |
| Pattern B3: | _frosinone2021t |
| Pattern Ra3: | _frosinone2021t |
| Pattern Sh3: | _frosinone2021t |
| Pattern So3: | _frosinone2021t |
| Leftarm3: | 000000 |
| Body3: | 000000 |
| Rightarm3: | 000000 |
| Shorts3: | 000000 |
| Socks3: | 000040 |
| Prevseason: | 2019–20 |
| Nextseason: | 2021–22 |
The 2020–21 season was Frosinone Calcio's third consecutive season in second division of the Italian football league, the Serie B, and the 115th as a football club.
See main article: 2020–21 Serie B.
The league fixtures were announced on 24 July 2021.[1]
See main article: 2020–21 Coppa Italia.