| Date: | November 10–17 |
| Edition: | 2nd |
| Surface: | Hard, outdoor |
| Prize Money: | $162,480+H (ATP) $162,480 (WTA) |
| Category: | ATP Challenger Tour WTA 125K series |
| Location: | Houston, United States |
| Venue: | George R. Brown Tennis Center |
| Champms: |  Marcos Giron |
| Champmd: |  Jonathan Erlich /  Santiago González |
| Champws: |  Kirsten Flipkens |
| Champwd: |  Ellen Perez /  Luisa Stefani |
The 2019 Oracle Challenger Series – Houston was a professional tennis tournament played on outdoor hard courts. This tournament was part of the 2019 ATP Challenger Tour and the 2019 WTA 125K series.[1] The second edition took place at the George R. Brown Tennis Center from November 10 to 17, 2019 in Houston, United States.[2]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Tennys Sandgren | 69 | 1 | ||
| Bradley Klahn | 105 | 2 | ||
| Ivo Karlović | 106 | 3 | ||
| Marcos Giron | 124 | 4 | ||
| Jason Jung | 130 | 5 | ||
| Australia | Christopher O'Connell | 140 | 6 | |
| Darian King | 165 | 7 | ||
| Mitchell Krueger | 196 | 8 | ||
 Russian Federation | Alexey Vatutin | 197 | 9 | |
| Donald Young | 233 | 10 | ||
 Spain | Adrián Menéndez Maceiras | 236 | 11 | |
 Serbia | Peđa Krstin | 238 | 12 | |
| Jenson Brooksby | 274 | 13 | ||
| Michael Mmoh | 294 | 14 | ||
| Michael Redlicki | 315 | 15 | ||
| Sekou Bangoura | 317 | 16 |
The following players received wildcards into the singles main draw:
Mohamed Abdel-Aziz Oliver Crawford Brandon Holt Zane Khan Sumit SarkarThe following players received entry from the qualifying draw:
Alafia Ayeni
Alexis Galarneau| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Danielle Collins | 31 | 1 | ||
| Taylor Townsend | 84 | 2 | ||
| Belgium | Kirsten Flipkens | 95 | 3 | |
 Ukraine | Katarina Zavatska | 110 | 4 | |
 Romania | ||||
| Caty McNally | 118 | 6 | ||
| Stefanie Vögele | 119 | 7 | ||
| Francesca Di Lorenzo | 121 | 8 | ||
| Whitney Osuigwe | 132 | 9 | ||
 Luxembourg | Mandy Minella | 137 | 10 | |
| Usue Maitane Arconada | 140 | 11 | ||
| Allie Kiick | 147 | 12 | ||
| Ann Li | 148 | 13 | ||
| Caroline Dolehide | 154 | 14 | ||
| Sachia Vickery | 158 | 15 | ||
| Varvara Lepchenko | 170 | 15 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw through protected ranking:
The following players received entry from the qualifying draw:
The following player received entry into the main draw as lucky loser:
Sara Errani → replaced by 
Fanny Stollár Jaimee Fourlis → replaced by Hanna Chang
Mayo Hibi → replaced by Kayla Day
Katarzyna Kawa → replaced by Grace Min
Kristína Kučová → replaced by Mari Osaka Anastasiya Komardina → replaced by Catherine Harrison Asia Muhammad → replaced by Deniz Khazaniuk Jessica Pegula → replaced by Hailey Baptiste Olivia Rogowska → replaced by Gabriela Cé Katherine Sebov → replaced by Giuliana Olmos
Katie Swan → replaced by 
Anna Danilina Patricia Maria Țig → replaced by Quinn Gleason| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Sharon Fichman | Japan | Ena Shibahara | 119 | 1 | ||
| Australia | Ellen Perez | Brazil | Luisa Stefani | 140 | 2 | |
| Mexico | Giuliana Olmos | Sabrina Santamaria | 143 | 3 | ||
| Hungary | Fanny Stollár | Taylor Townsend | 180 | 4 |
The following pair received a wildcard into the doubles main draw:
Hailey Baptiste / Ellie DouglasSee main article: article and 2019 Oracle Challenger Series – Houston – Men's singles.
Marcos Giron def Ivo Karlović 7–5, 6–7(5–7), 7–6(11–9).See main article: article and 2019 Oracle Challenger Series – Houston – Women's singles.
Kirsten Flipkens def. CoCo Vandeweghe 7–6(7–4), 6–4See main article: article and 2019 Oracle Challenger Series – Houston – Men's doubles.
Jonathan Erlich / Santiago González def. Ariel Behar / 
Gonzalo Escobar 6–3, 7–6(7–4).See main article: article and 2019 Oracle Challenger Series – Houston – Women's doubles.
Ellen Perez / Luisa Stefani def. Sharon Fichman / Ena Shibahara, 1–6, 6–4, [10–5]