| Champ: |  Dylan Alcott |
| Runner: |  David Wagner |
| Score: | 6–4, 7–6(7–2) |
| Before Name: | Australian Open – Wheelchair quad singles |
See main article: 2019 Australian Open.
Four-time defending champion Dylan Alcott defeated David Wagner in the final, 6–4, 7–6(7–2) to win the quad singles wheelchair tennis title at the 2019 Australian Open.