| Champ: | Petra Martić |
| Runner: |  Markéta Vondroušová |
| Score: | 1–6, 6–4, 6–1 |
| Draw: | 32 |
| Seeds: | 8 |
| Type: | singles doubles |
| Before Name: | İstanbul Cup – Singles |
| After Name: | İstanbul Cup – Singles |
See main article: 2019 İstanbul Cup.
Pauline Parmentier was the defending champion,[1] but lost in the second round to Elena Rybakina.
Petra Martić won her first WTA Tour title, defeating Markéta Vondroušová in the final, 1–6, 6–4, 6–1.