| Champ: | Marcelo Arévalo |
| Runner: |  Roberto Cid Subervi |
| Score: | 6–3, 6–7(3–7), 6–4 |
| Type: | singles doubles |
See main article: article and 2018 San Luis Open Challenger Tour.
Andrej Martin was the defending champion but chose not to defend his title.
Marcelo Arévalo won the title after defeating Roberto Cid Subervi 6–3, 6–7(3–7), 6–4 in the final.