The 2016 Indiana State Sycamores football team represented Indiana State University in the 2016 NCAA Division I FCS football season. They were led by fourth-year head coach Mike Sanford and played their home games at Memorial Stadium. They were a member of the Missouri Valley Football Conference. They finished the season 4–7, 2–6 in MVFC play to finish in a three-way tie for eighth place.
On December 16, head coach Mike Sanford resigned[1] to join the staff at WKU where his son, Mike Sanford Jr., had recently been named the head coach. Sanford leaves Indiana State with a four year record of 18–30.
See also: 2016 Butler Bulldogs football team.
See also: 2016 Minnesota Golden Gophers football team.
See also: 2016 Southeast Missouri State Redhawks football team.
See also: 2016 Illinois State Redbirds football team.
See also: 2016 Missouri State Bears football team.
See also: 2016 Western Illinois Leathernecks football team.
See also: 2016 South Dakota Coyotes football team.
See also: 2016 Southern Illinois Salukis football team.
See also: 2016 Youngstown State Penguins football team.
See also: 2016 Northern Iowa Panthers football team.
See also: 2016 North Dakota State Bison football team.