The 2012 Tashkent Open was a women's tennis tournament played on outdoor hard courts. It was the 14th edition of the Tashkent Open, and was part of the WTA International tournaments of the 2012 WTA Tour. It took place at the Tashkent Tennis Center in Tashkent, Uzbekistan, from September 10 through September 16, 2012. Unseeded Irina-Camelia Begu won the singles title.
See main article: 2012 Tashkent Open – Singles. 
Irina-Camelia Begu defeated Donna Vekić, 6–4, 6–4
See main article: 2012 Tashkent Open – Doubles. 
Paula Kania / 
Polina Pekhova defeated 
Anna Chakvetadze / 
Vesna Dolonc, 6–2, ret.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Romania | Monica Niculescu | 33 | 1 | |
| Poland | Urszula Radwańska | 43 | 2 | |
 France | Alizé Cornet | 50 | 3 | |
 Slovakia | Magdaléna Rybáriková | 66 | 4 | |
| Romania | Alexandra Cadanțu | 68 | 5 | |
| Serbia | Bojana Jovanovski | 72 | 6 | |
| Russian Federation | Alexandra Panova | 76 | 7 | |
 Kazakhstan | Galina Voskoboeva | 80 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Kateryna Bondarenko Stéphanie Foretz Gacon
Shahar Pe'er Ksenia Pervak| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Romania | Irina-Camelia Begu | Romania | Monica Niculescu | 65 | 1 | |
| Russian Federation | Nina Bratchikova | Russian Federation | Alexandra Panova | 135 | 2 | |
 Czech Republic | Eva Birnerová | Eleni Daniilidou | 138 | 3 | ||
| France | Alizé Cornet | Russian Federation | Alla Kudryavtseva | 149 | 4 |
The following pairs received wildcards into the doubles main draw:
Nigina Abduraimova / Ksenia Lykina Daria Gavrilova / Sabina Sharipova Anna Chakvetadze (back injury)