The 2012 Seguros Bolívar Open Pereira was a professional tennis tournament played on clay courts. It was the fourth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Pereira, Colombia between 9 and 15 April 2012.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Colombia | Santiago Giraldo | 55 | 1 | |
| Colombia | Alejandro Falla | 56 | 2 | |
 Spain | Rubén Ramírez Hidalgo | 125 | 3 | |
 Argentina | Martín Alund | 169 | 4 | |
 Dominican Republic | Víctor Estrella | 203 | 5 | |
| Argentina | Guido Pella | 204 | 6 | |
| Colombia | Carlos Salamanca | 245 | 7 | |
| Colombia | Eduardo Struvay | 247 | 8 |
The following players received wildcards into the singles main draw:
Felipe Escobar Alejandro Falla Sebastian SerranoThe following players received entry from the qualifying draw:
See main article: 2012 Seguros Bolívar Open Pereira – Singles.
Carlos Salamanca def. Rubén Ramírez Hidalgo, 5–7, 6–2, 6–1See main article: 2012 Seguros Bolívar Open Pereira – Doubles.
Martín Alund / Guido Pella def. Sebastián Decoud / Rubén Ramírez Hidalgo, 6–3, 2–6, [10–5]
