The 2011 U.S. Men's Clay Court Championships was a men's tennis tournament played on outdoor clay courts. It was the 43rd edition of the U.S. Men's Clay Court Championships, and was an ATP World Tour 250 event. It took place at River Oaks Country Club in Houston, Texas, United States, from April 4 through April 10, 2011. Unseeded Ryan Sweeting, who entered the main draw on a wildcard, won the singles title.
See main article: 2011 U.S. Men's Clay Court Championships – Singles. 
Ryan Sweeting defeated 
Kei Nishikori, 6–4, 7–6(7–3)
See main article: 2011 U.S. Men's Clay Court Championships – Doubles. Bob Bryan / Mike Bryan defeated John Isner / Sam Querrey, 6–7(4–7), 6–2, [10–5]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| United States | Mardy Fish | 15 | 1 | |
| United States | Sam Querrey | 21 | 2 | |
 Spain | Guillermo García-López | 26 | 3 | |
| United States | John Isner | 33 | 4 | |
| Benjamin Becker | 58 | 5 | ||
| Japan | Kei Nishikori | 62 | 6 | |
| Pablo Cuevas | 67 | 7 | ||
| Grigor Dimitrov | 70 | 8 |
The following players received wildcards into the main draw:
The following players received entry via qualifying:
See main article: 2011 U.S. Men's Clay Court Championships – Singles qualifying.
Juan Ignacio Chela (personal reasons)[2]
Lleyton Hewitt (foot surgery)[3]
Denis Istomin