| Primera División de México | |
| Year: | 2010 |
| Country: | Mexico |
| Num Teams: | 8 |
| Champions: | Monterrey |
| Runner-Up: | Santos Laguna |
| Matches: | 14 |
| Goals: | 40 |
| Top Goal Scorer: | Humberto Suazo (5 goals) |
| Prevseason: | 2010 Bicentenario |
| Nextseason: | 2011 Clausura |
The Liguilla (en|Mini League) of the 2010 Primera División de México Apertura was a final knockout tournament involving eight teams of the Primera División de México. The tournament began on November 17, 2010, and concluded on December 5, 2010, with Monterrey beating Santos Laguna 5 - 3 on aggregate over two legs.[1]
The 18 teams that participated in the 2010 Apertura were divided into three groups of six teams. The top two in each group qualify automatically. The two best teams in the general table not already qualified, regardless of group, qualify as well.
| width=25; rowspan=2 | width=100; rowspan=2 | Team | width=175; rowspan=2 | Manager | width=150; rowspan=2 | Captain | Performance at the Apertura 2010 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| width=30 | width=30 | width=30 | width=30 | width=30 | width=30 | width=30 | width=30 | width=40 | width=140 | Qualified as | |||||||||
| 1 | Cruz Azul |  Enrique Meza | Gerardo Torrado | 17 | 12 | 3 | 2 | 33 | 13 | +20 | 39 | 1st | First place Group 3 | ||||||
| 2 | Monterrey | Víctor Vucetich | Luis Ernesto Pérez | 17 | 9 | 5 | 3 | 29 | 20 | +9 | 32 | 2nd | First place Group 1 | ||||||
| 3 | Santos Laguna |  Rubén Omar Romano | Oswaldo Sánchez | 17 | 9 | 3 | 5 | 29 | 19 | +11 | 30 | 3rd | Runner-up Group 1 | ||||||
| 4 | América | Manuel Lapuente | Pável Pardo | 17 | 7 | 6 | 4 | 22 | 16 | +6 | 27 | 4th | First place Group 2 | ||||||
| 5 | San Luis | Ignacio Ambríz | Ignacio Torres | 17 | 8 | 2 | 7 | 21 | 19 | +2 | 26 | 5th | Runner-up Group 2 | ||||||
| 6 | Chiapas | Jose Guadalupe Cruz | Christian Valdéz | 17 | 6 | 7 | 4 | 21 | 14 | +7 | 25 | 6th | Runner-up Group 3 | ||||||
| 7 | Pachuca | Pablo Marini |  Miguel Calero | 17 | 7 | 4 | 6 | 27 | 28 | -1 | 25 | 7th | Third place Group 2 | ||||||
| 8 | UNAM | Guillermo Vázquez | Sergio Bernal | 17 | 7 | 4 | 6 | 23 | 24 | -1 | 25 | 8th | Third place Group 3 | ||||||
The eight qualified teams play two games against each other on a home-and-away basis. The winner of each match up is determined by aggregate score.
The teams were seeded one to eight in quarterfinals, and will be re-seeded one to four in semifinals, depending on their position in the general table. The higher seeded teams play on their home field during the second leg.
The first legs of the quarterfinals were played on November 17 and 18. The second legs were played on November 20 and 21.
Kickoffs are given in local time (UTC-6).
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The first legs of the semifinals were played on November 25. The second legs were played on November 28.
Kickoffs are given in local time (UTC-6).
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The first leg of the final was played on December 2. The second leg was played on December 5.
Kickoffs are given in local time (UTC-6).