| Champ: |  Mariana Duque Mariño |
| Runner: | Angelique Kerber |
| Score: | 6 - 4, 6 - 3 |
| Type: | singles doubles |
| Main Name: | Copa Colsanitas |
| Before Name: | Copa Sony Ericsson Colsanitas |
| After Name: | Copa Sony Ericsson Colsanitas |
See main article: 2010 Copa BBVA-Colsanitas. María José Martínez Sánchez was the defending champion, but chose to compete in the 2010 Dubai Tennis Championships instead.
Mariana Duque Mariño won in the final 6 - 4, 6 - 3, against Angelique Kerber.