| Champ: |  Marinko Matosevic |
| Runner: |  Ryan Sweeting |
| Score: | 2–6, 6–4, 6–3 |
| Type: | singles doubles |
See main article: 2010 Calabasas Pro Tennis Championships. Donald Young was the defending champion; however, he was eliminated by Marinko Matosevic in the semifinals.
Matosevic won in the final match 2–6, 6–4, 6–3, against Ryan Sweeting.