See main article: 2010 BNP Paribas Open. Victoria Azarenka and Vera Zvonareva were the defending champions. Azarenka chose not to compete and Zvonareva partnered with Lucie Šafářová.
Zvonareva lost in the first round to the wildcard team of Jelena Janković and Tathiana Garbin.
The unseeded pair Květa Peschke and Katarina Srebotnik won in the final 6–4, 2–6, [10–5], against Nadia Petrova and Samantha Stosur.