| Competition: | 2. česká fotbalová liga |
| Season: | 2010–11 |
| Winners: | FK Dukla Prague |
| Promoted: | FK Dukla Prague Viktoria Žižkov |
| Relegated: | Kladno Hlučín |
| League Topscorer: | Dani Chigou (19) |
| Biggest Home Win: | Jihlava 6–1 Čáslav FK Dukla Prague 5–0 Čáslav Karviná 5–0 Čáslav |
| Biggest Away Win: | Hlučín 0–5 Vlašim |
| Highest Scoring: | Kladno 5–3 Most |
| Matches: | 240 |
| Total Goals: | 649 |
| Prevseason: | 2009–10 |
| Nextseason: | 2011–12 |
The 2010–11 Czech 2. Liga was the 18th season of the 2. česká fotbalová liga, the second tier of the Czech football league. The season began on 30 July 2010 and ended on 11 June 2011. The winter break was scheduled between 6 November 2010 and 5 March 2011.
FK Dukla Prague secured the 2. Liga title on 27 May 2011.[1] Viktoria Žižkov were confirmed as the second team to gain promotion to the Czech First League on 4 June 2011.[2] Hlučín, finishing last, were the first team to be relegated. Kladno were relegated in 15th position, their second consecutive relegation, on 4 June 2011.[2]
Promoted to Czech First League
Relegated to Moravian-Silesian Football League
Relegated from Czech First League
Promoted from Bohemian Football League
Promoted from Moravian-Silesian Football League
| Club | Location | Stadium | Capacity | 2009-10 Position | |
|---|---|---|---|---|---|
| Čáslav | Čáslav | 2,575 | 14th | ||
| FK Dukla Prague | Prague | 18,000 | 6th | ||
| Hlučín | Hlučín | 2,380 | 13th | ||
| Jihlava | Jihlava | 4,075 | 4th | ||
| Karviná | Karviná | 8,000 | 8th | ||
| Kladno | Kladno | 4,000 | 15th in Czech First League | ||
| Most | Most | 7,500 | 11th | ||
| Sezimovo Ústí | Sezimovo Ústí | 900 | 1st in ČFL | ||
| Sokolov | Sokolov | 5,000 | 10th | ||
| Sparta Prague B | Prague | 3,400 | 12th | ||
| Třinec | Třinec | 2,200 | 9th | ||
| Varnsdorf | Varnsdorf | 5,000 | 6th in ČFL | ||
| Viktoria Žižkov | Prague | 5,600 | 5th | ||
| Vlašim | Vlašim | 6,000 | 7th | ||
| Zlín | Zlín | 6,375 | 3rd | ||
| Znojmo | Znojmo | 5,000 | 1st in MSFL |
Final standings.
| Rank | Scorer | Club | Goals |
|---|---|---|---|
| 1 |  Dani Chigou | Dukla Prague | 19 |
| 2 |  Miroslav Marković | Viktoria Žižkov | 17 |
| 3 |  Miroslav Podrazký | Sokolov | 12 |
| Miloslav Strnad | Vlašim | 12 | |
| 5 | Filip Dort | Jihlava | 11 |
| Petr Wojnar | Kladno | 11 | |
| Jiří Mlika | Sokolov | 11 |