| Competition: | Serbian League East |
| Season: | 2009–10 |
| Winners: | Sinđelić |
| Promoted: | Sinđelić |
| Relegated: | Jedinstvo (B) Župa Balkanski |
| Matches: | 240 |
| Total Goals: | 687 |
| Biggest Home Win: | Radnički (P) 6–0 Rudar (8 November 2009) |
| Biggest Away Win: | Jedinstvo (B) 0–4 Timok (17 October 2009) Župa 0–4 Sinđelić (29 May 2010) |
| Highest Scoring: | Balkanski 5–3 Dubočica (6 June 2010) |
| Prevseason: | 2008–09 |
| Nextseason: | 2010–11 |
The 2009–10 Serbian League East season was the seventh season of the league under its current title. It began on 15 August 2009 and ended on 6 June 2010.