| Competition: | Serbian League East |
| Season: | 2007–08 |
| Winners: | Dinamo Vranje |
| Promoted: | Dinamo Vranje |
| Relegated: | OFK Niš Rudar Aleksinac Ozren Sokobanja Sloga Leskovac Trayal Morava Vladičin Han |
| League Topscorer: | Novica Lazarević |
| Prevseason: | 2006–07 |
| Nextseason: | 2008–09 |
The 2007–08 Serbian League East season was the fifth season of the league under its current title. It began in August 2007 and ended in May 2008.