| Competition: | Eerste Klasse |
| Season: | 2005–6 |
| Relegated: | 2006–07 Tweede Klasse |
| Promotion To: | 2006–07 Hoofdklasse |
| Prevseason: | 2004–05 |
| Nextseason: | 2006–07 |
2005–06 Eerste Klasse was a Dutch association football season of the Eerste Klasse.
Saturday champions were:
Sunday champions were: