See main article: 2000 Tennis Masters Cup.
Gustavo Kuerten defeated Andre Agassi in the final, 6–4, 6–4, 6–4 to win the singles tennis title at the 2000 Tennis Masters Cup. With the win, Kuerten became the year-end No. 1, and became the first South American to make the achievement.
Pete Sampras was the defending champion, but was defeated in the semifinals by Kuerten.
Standings are determined by: 1. number of wins; 2. number of matches; 3. in two-players-ties, head-to-head records; 4. in three-players-ties, percentage of sets won, or of games won; 5. steering-committee decision.
Standings are determined by: 1. number of wins; 2. number of matches; 3. in two-players-ties, head-to-head records; 4. in three-players-ties, percentage of sets won, or of games won; 5. steering-committee decision.