| Competition: | Serie C2 |
| Season: | 1988–89 |
| Winners: | Casale Chievo Fidelis Andria Campania Puteolana |
| Relegated: | Ilva Voghera Sorso Ospitaletto (repecheaged) Pordenone Giorgione Riccione (repecheaged) San Marino Bisceglie (repecheaged) Sorrento Benevento Cynthia Gela Afragolese Juve Stabia |
| Matches: | 1226 |
| Prevseason: | 1987–88 |
| Nextseason: | 1989–90 |
The 1988–89 Serie C2 was the eleventh edition of Serie C2, the fourth highest league in the Italian football league system.
A total of 72 teams contested the league, divided into four groups (in Italian: Gironi) of 18 teams.