| Competition: | Uganda National League |
| Season: | 1980 |
| Winners: | Nile Breweries |
| League Topscorer: | Davis Kamoga, Kampala City Council FC (21) |
| Prevseason: | 1979 |
| Nextseason: | 1981 |
The 1980 Uganda National League was the 13th season of the Ugandan football championship, the top-level football league of Uganda.
The 1980 Uganda National League was contested by 16 teams and was won by Nile Breweries from Jinja, while COOPS, Mbarara and Bell FC were relegated.
The top goalscorer in the 1980 season was Davis Kamoga of Kampala City Council FC with 21 goals.