| Club: | Partizan |
| Season: | 1980–81[1] |
| Chairman: | Vlada Kostić |
| Chrtitle: | President |
| Manager: | Tomislav Kaloperović |
| Mgrtitle: | Head coach |
| League: | Yugoslav First League |
| League Result: | 8th |
| Cup1: | Yugoslav Cup |
| Cup1 Result: | Semi-finals |
| Prevseason: | 1979–80 |
| Nextseason: | 1981–82 |
The 1980–81 season was the 35th season in FK Partizan's existence. This article shows player statistics and matches that the club played during the 1980–81 season.
See main article: 1980–81 Yugoslav Cup.