| Year: | 1972 |
| Team: | Wyoming Cowboys |
| Sport: | football |
| Conference: | Western Athletic Conference |
| Short Conf: | WAC |
| Record: | 4–7 |
| Conf Record: | 3–4 |
| Head Coach: | Fritz Shurmur |
| Hc Year: | 2nd |
| Captain: | Nick Bebout, Ed Schmidt |
| Stadium: | War Memorial Stadium |
The 1972 Wyoming Cowboys football team represented the University of Wyoming as a member of the Western Athletic Conference (WAC) during the 1972 NCAA University Division football season. Led by second-year head coach Fritz Shurmur, the Cowboys compiled a record of 4–7 (3–4 against conference opponents), placing fifth in the WAC. The team played home games on campus at War Memorial Stadium in Laramie, Wyoming.