The 50° Targa Florio took place on 8 May 1966, on the Circuito Piccolo delle Madonie, Sicily (Italy).[1]
The 50th anniversary edition of the Targa was marred by an inclement weather that turned the road into a quagmire. The winners of the 1965 edition, Nino Vaccarella and Lorenzo Bandini started as favorites driving the powerful, prototype-class Ferrari 330 P3.[1] Indeed it seemed they could led Ferrari to another victory but two laps from the end, a wrong maneuver by Bandini while lapping a slower car resulted in the 330 off the road. This paved the way of the victory for the factory-backed Scuderia Filipinetti Porsche 906 of Herbert Müller and Willy Mairesse, followed by the Dino 206 S of Guichet/Baghetti, and another 906 of Sicilian duo Pucci/Arena.[1]
| Pos | Class | No | Team | Drivers | Chassis | Laps | |
|---|---|---|---|---|---|---|---|
| 1 | S 2.0 | 148 | Scuderia Filipinetti/Porsche System Engineering | Herbert Müller Willy Mairesse | Porsche 906 | 10 | |
| 2 | P 2.0 | 196 |  Ferrari SEFAC |  Jean Guichet Giancarlo Baghetti | Dino 206 S | 10 | |
| 3 | S 2.0 | 144 | Porsche System Engineering | Antonio Pucci Vincenzo Arena | Porsche 906 | 10 |