| Competition: | Primera División |
| Season: | 1965 |
| Winners: | Boca Juniors (16th title) |
| Promoted: | Lanús Platense |
| Relegated: | (none) |
| Continentalcup1: | 1966 Copa Libertadores |
| Continentalcup1 Qualifiers: | Boca Juniors River Plate |
| League Topscorer: |  Juan Carlos Carone (19 goals) |
| Prevseason: | 1964 |
| Nextseason: | 1966 |
The 1965 Argentine Primera División was the 74th season of top-flight football in Argentina. The season began on April 18 and ended on December 19.[1]
There were 18 teams in the tournament, who competed in a single double round-robin tournament. Boca Juniors won its 16th league title with no teams relegated.