| Election Name: | 1964 United States Senate election in Maine |
| Country: | Maine |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1958 United States Senate election in Maine |
| Previous Year: | 1958 |
| Next Election: | 1970 United States Senate election in Maine |
| Next Year: | 1970 |
| Election Date: | November 3, 1964 |
| Image1: | Edmund Muskie.jpg |
| Nominee1: | Edmund Muskie |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 253,511 |
| Percentage1: | 66.62% |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 127,040 |
| Percentage2: | 33.38% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Party: | Democratic Party (US) |
| After Party: | Democratic Party (US) |
The 1964 United States Senate election in Maine was held on November 3, 1964. Incumbent Democrat Edmund Muskie was re-elected to a second term in office over Republican U.S. Representative Clifford McIntire. This was the first senate race for this particular seat in which the election was held in November and not September. This was the first time ever that an incumbent Democratic Senator from Maine was re-elected to a second full term.
Senator Muskie was unopposed for re-nomination.
Representative McIntire was unopposed for the Republican nomination.