| Year: | 1959 |
| Team: | South Carolina Gamecocks |
| Sport: | football |
| Conference: | Atlantic Coast Conference |
| Short Conf: | ACC |
| Record: | 6–4 |
| Conf Record: | 4–3 |
| Head Coach: | Warren Giese |
| Hc Year: | 4th |
| Captain: | John Saunders, Ed Pitts |
| Stadium: | Carolina Stadium |
The 1959 South Carolina Gamecocks football team represented the University of South Carolina as a member of the Atlantic Coast Conference (ACC) during the 1959 college football season. Led by fourth-year head coach Warren Giese, the Gamecocks compiled an overall record of 6–4 with a mark of 4–3 in conference play, tying for fourth place in the ACC. The team played home games at Carolina Stadium in Columbia, South Carolina.