| Election Name: | 1958 United States Senate election in Pennsylvania |
| Country: | Pennsylvania |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1952 United States Senate election in Pennsylvania |
| Previous Year: | 1952 |
| Next Election: | 1964 United States Senate election in Pennsylvania |
| Next Year: | 1964 |
| Election Date: | November 4, 1958 |
| Image1: | Image:Hugh Scott.jpg |
| Nominee1: | Hugh Scott |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 2,042,586 |
| Percentage1: | 51.21% |
| Nominee2: | George M. Leader |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 1,929,821 |
| Percentage2: | 48.38% |
| Map Size: | 260px |
| U.S. Senator | |
| Before Election: | Edward Martin |
| Before Party: | Republican Party (United States) |
| After Election: | Hugh Scott |
| After Party: | Republican Party (United States) |
The 1958 United States Senate election in Pennsylvania was held on November 4, 1958. Incumbent Republican U.S. Senator Edward Martin did not seek re-election. The Republican nominee, Hugh Scott, defeated Democratic nominee George M. Leader for the vacant seat.
As of, this is the last Senate election where Fulton County voted Democratic.
|-|-bgcolor="#EEEEEE"| colspan="3" align="right" | Totals| align="right" | 3,988,622| align="right" | 100.00%| align="right" | |}