| Year: | 1951 |
| Team: | USC Trojans |
| Sport: | football |
| Conference: | Pacific Coast Conference |
| Short Conf: | PCC |
| Record: | 7–3 |
| Conf Record: | 4–2 |
| Head Coach: | Jess Hill |
| Hc Year: | 1st |
| Stadium: | Los Angeles Memorial Coliseum |
The 1951 USC Trojans football team represented the University of Southern California (USC) as a member of the Pacific Coast Conference (PCC_) during the 1951 college football season. Led by first year head coach Jess Hill, the Trojans compiled an overall record of 7–3 with a mark of 4–2 in conference play, placing fourth in the PCC. USC played home games at Los Angeles Memorial Coliseum in Los Angeles.
The following players were drafted into professional football following the season.
| Player | Position | Round | Pick | Franchise |
| Frank Gifford | Running back | 1 | 11 | |
| Pat Cannamela | 11 | 122 | ||
| Bob Hooks | End | 16 | 193 | |
| Al Baldock | End | 17 | 201 | San Francisco 49ers |
| Dean Schneider | Back | 22 | 254 | New York Giants |