| Election Name: | 1950 United States Senate election in Kentucky |
| Country: | Kentucky |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1944 United States Senate election in Kentucky |
| Previous Year: | 1944 |
| Next Election: | 1956 United States Senate election in Kentucky |
| Next Year: | 1956 |
| Election Date: | November 7, 1950 |
| Image1: | File:Earle-Clements.jpg |
| Nominee1: | Earle Clements |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 334,249 |
| Percentage1: | 54.2% |
| Nominee2: | Charles I. Dawson |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 278,368 |
| Percentage2: | 45.1% |
| Map Size: | 300px |
| U.S. Senator | |
| Before Election: | Earle Clements |
| Before Party: | Democratic Party (United States) |
| After Election: | Earle Clements |
| After Party: | Democratic Party (United States) |
Two United States Senate elections for the Class 3 U.S. Senate seat from Kentucky were held simultaneously on November 7, 1950.
After Senator Alben Barkley resigned on January 19, 1949, to become Vice President of the United States, Governor Earle Clements appointed Garrett L. Withers to fill the vacant seat until a successor could be duly elected to complete the expired term. The special election was scheduled for November 7, 1950, concurrent with the regular election to the next term. Clements appointed Withers with the intention of running for the seat himself, which he did, defeating Republican former judge Charles I. Dawson in both elections.