| Election Name: | 1946 United States Senate election in Tennessee |
| Country: | Tennessee |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1940 United States Senate election in Tennessee |
| Previous Year: | 1940 |
| Next Election: | 1952 United States Senate election in Tennessee |
| Next Year: | 1952 |
| Election Date: | November 5, 1946 |
| Nominee1: | Kenneth McKellar |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 145,654 |
| Percentage1: | 66.60% |
| Nominee2: | William B. Ladd |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 57,237 |
| Percentage2: | 26.17% |
| Nominee3: | John Randolph Neal Jr. |
| Party3: | Independent (politician) |
| Popular Vote3: | 11,516 |
| Percentage3: | 5.27% |
| Map Size: | 300px |
| U.S. senator | |
| Before Election: | Kenneth McKellar |
| Before Party: | Democratic Party (US) |
| After Election: | Kenneth McKellar |
| After Party: | Democratic Party (US) |
The 1946 United States Senate election in Tennessee was held on November 5, 1946. Incumbent Democratic Senator Kenneth D. McKellar was re-elected to a sixth term in office. He defeated a primary challenge by Edward W. Carmack Jr. and easily won the general election against Republican William B. Ladd, and Independent candidate John Randolph Neal Jr.