| Year: | 1916 |
| Team: | Wyoming Cowboys |
| Sport: | football |
| Conference: | Rocky Mountain Conference |
| Short Conf: | RMC |
| Record: | 1–4 |
| Conf Record: | 1–4 |
| Head Coach: | John Corbett |
| Hc Year: | 2nd |
| Captain: | L. E. Mau |
The 1916 Wyoming Cowboys football team was an American football team that represented the University of Wyoming as a member of the Rocky Mountain Conference (RMC) during the 1916 college football season. In their second season under head coach John Corbett, the Cowboys compiled a 1–4 record with all games against conference opponents, place sixth in the RMC, and were outscored by a total of 115 to 50. L. E. Mau was the team captain.[1] [2]