| Election Name: | 1859 Ohio gubernatorial election |
| Country: | Ohio |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1857 Ohio gubernatorial election |
| Previous Year: | 1857 |
| Next Election: | 1861 Ohio gubernatorial election |
| Next Year: | 1861 |
| Election Date: | October 11, 1859 |
| Nominee1: | William Dennison Jr. |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 184,557 |
| Percentage1: | 51.87% |
| Nominee2: | Rufus P. Ranney |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 171,226 |
| Percentage2: | 48.13% |
| Map Size: | 210px |
| Governor | |
| Before Election: | Salmon P. Chase |
| Before Party: | Republican Party (United States) |
| After Election: | William Dennison Jr. |
| After Party: | Republican Party (United States) |
The 1859 Ohio gubernatorial election was held on October 11, 1859. Republican nominee William Dennison Jr. defeated Democratic nominee Rufus P. Ranney with 51.87% of the vote.