Tennessee elected its members August 9–10, 1821, after the term began but before the new Congress convened.
| District | Incumbent | This race | ||||||
|---|---|---|---|---|---|---|---|---|
| Member | Party | First elected | Results | Candidates | ||||
| John Rhea | Democratic-Republican | 1803 1815 (Lost) 1817 | Incumbent re-elected. | nowrap | ||||
| John Cocke | Democratic-Republican | 1819 | Incumbent re-elected. | nowrap | ||||
| Francis Jones | Democratic-Republican | 1817 | Incumbent re-elected. | nowrap | ||||
| Robert Allen | Democratic-Republican | 1819 | Incumbent re-elected. | nowrap | ||||
| Newton Cannon | Democratic-Republican | 1814 (Special) 1817 (Lost) 1819 | Incumbent re-elected. | nowrap | ||||
| Henry H. Bryan | Democratic-Republican | 1819 | Incumbent re-elected. Winner never appeared to take his seat. | nowrap | ||||